Open AccessGrowth of <i>Bifidobacterium</i> species is inhibited by free fatty acids and bile salts but not by glycerides
Author(s) -
Sergio Pérez-Burillo,
Sumudu Rajakaruna,
Oleg Paliy
Publication year - 2022
Publication title -
aims microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.565
H-Index - 6
ISSN - 2471-1888
DOI - 10.3934/microbiol.2022005
Subject(s) - chemistry , glyceride , oleic acid , biology , food science , biochemistry , fatty acid
High-fat diets have been associated with lower gut and fecal abundances of genus Bifidobacterium . Here, we investigated whether commonly consumed dietary free fatty acids have any detrimental effect on the growth of B. adolescentis , B. bifidum , and B. longum . We found that the presence of free fatty acids in the medium inhibits the growth of Bifidobacterium species to a varying degree, with capric (C10:0), oleic (C18:1), and linoleic (C18:2) acids displaying the largest effect. In comparison, free fatty acids did not affect the growth of Escherichia coli . When fats were added as a mixture of mono- and diacylglycerols, the inhibitory effect on Bifidobacterium growth was abolished.