Open AccessRobust rank aggregation and cibersort algorithm applied to the identification of key genes in head and neck squamous cell cancer
Author(s) -
Tingting Chen,
Wei Hua,
Bing Xu,
Hui Chen,
Minhao Xie,
Xinchen Sun,
Xiaolin Ge
Publication year - 2021
Publication title -
mathematical biosciences and engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.451
H-Index - 45
eISSN - 1551-0018
pISSN - 1547-1063
DOI - 10.3934/mbe.2021228
Subject(s) - kegg , head and neck squamous cell carcinoma , gene , biology , computational biology , cancer , bioinformatics , cancer research , head and neck cancer , gene expression , genetics , transcriptome
Although multiple hub genes have been identified in head and neck squamous cell cancer (HNSCC) in recent years, because of the limited sample size and inconsistent bioinformatics analysis methods, the results are not reliable. Therefore, it is urgent to use reliable algorithms to find new prognostic markers of HNSCC.