Open AccessA mathematical model studying mosquito-stage transmission-blocking vaccines
Author(s) -
Ruijun Zhao,
Jemal Mohammed-Awel
Publication year - 2014
Publication title -
mathematical biosciences and engineering
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.451
H-Index - 45
eISSN - 1551-0018
pISSN - 1547-1063
DOI - 10.3934/mbe.2014.11.1229
Subject(s) - blocking (statistics) , malaria , stage (stratigraphy) , transmission (telecommunications) , epidemic model , computer science , disease transmission , virology , biology , mathematical optimization , mathematics , immunology , medicine , environmental health , computer network , paleontology , telecommunications , population
A compartmental deterministic model is proposed to evaluate the effectiveness of transmission-blocking vaccines of malaria, which targets at the parasite stage in the mosquito. The model is rigorously analyzed and numerical simulations are performed. The results and implications are discussed.