Open AccessCost-effectiveness analysis on measles transmission with vaccination and treatment intervention
Author(s) -
Shinta A. Rahmayani,
Dipo Aldila,
Bevina D. Handari
Publication year - 2021
Publication title -
aims mathematics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 15
ISSN - 2473-6988
DOI - 10.3934/math.2021721
Subject(s) - measles , vaccination , basic reproduction number , measles vaccine , medicine , transmission (telecommunications) , intervention (counseling) , qualitative analysis , cost effectiveness analysis , mathematics , demography , computer science , environmental health , virology , risk analysis (engineering) , qualitative research , cost effectiveness , population , nursing , telecommunications , social science , sociology
A deterministic model which describes measles' dynamic using newborns and adults first and second dose of vaccination and medical treatment is constructed in this paper. Mathematical analysis about existence of equilibrium points, basic reproduction number, and bifurcation analysis conducted to understand qualitative behaviour of the model. For numerical purposes, we estimated the parameters' values of the model using monthly measles data from Jakarta, Indonesia. Optimal control theory was applied to investigate the optimal strategy in handling measles spread. The results show that all controls succeeded in reducing the number of infected individuals. The cost-effective analysis was conducted to determine the best strategy to reduce number of infected individuals with the lowest cost of intervention. Our result indicates that the use of the first dose measles vaccine with medical treatment is the most optimal strategy to control measles transmission.