Open AccessVisual Capacity and Prader-Willi Syndrome
Author(s) -
Robert Fox,
Robbin B. Sinatra,
Megan A. Mooney,
Irene D. Feurer,
Merlin G. Butler
Publication year - 1999
Publication title -
journal of pediatric ophthalmology and strabismus
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.416
H-Index - 46
eISSN - 1938-2405
pISSN - 0191-3913
DOI - 10.3928/0191-3913-19991101-08
Subject(s) - medicine , hypotonia , abnormality , pediatrics , coloboma , short stature , incidence (geometry) , ophthalmology , physics , psychiatry , optics
Prader-Willi syndrome (PWS) refers to a genetic disorder induced by an anomaly on chromosome 15 occurring with a frequency of one in 10,000 to 20,000. It is characterized by a unique set of features including infantile hypotonia, obesity in childhood, small hands and feet, hypogonadism, and mental retardation. Reported here are the results of ophthalmic examinations of persons with PWS, together with results from controls comparable in age, percentage of body fat, and intelligence. These data bear on the hypothesis that the ocular anomalies in PWS are unique to this syndrome.