In vitro and in vivo Antibacterial Activity of Cheilocostus speciosus Rhizome Extract on Resistant Bacteria

Cheilocostus speciosus has traditionally been used in alternative medicine for different therapeutic purposes in different countries, including as an anti-infective agent. Antimicrobial properties of C. speciosus against standard bacterial strains have been reported before, however, complementary in vivo investigations, as well as, its antimicrobial activity against multi drug-resistant (MDR) bacteria are insufficient, if not lacking. In our study, in vitro and in vivo methods were used to test its antimicrobial activities on prominent clinical MDR isolates.