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Association of Perforin and Granzyme-B Levels with Hyperandrogenism in Polycystic Ovary Syndrome: A Case-Control Study
Author(s) -
Elham Zarei,
Hassan Mohajery,
Fatemeh Aliakbari,
Fatemeh Mohammad Zadeh,
Gholamreza Veghari,
Azad Reza Mansourian
Publication year - 2019
Publication title -
pakistan journal of biological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 43
eISSN - 1812-5735
pISSN - 1028-8880
DOI - 10.3923/pjbs.2019.393.399
Subject(s) - perforin , polycystic ovary , granzyme b , medicine , endocrinology , hyperandrogenism , dehydroepiandrosterone sulfate , free androgen index , hormone , biology , androgen , immunology , insulin , insulin resistance , cd8 , immune system
Polycystic ovary syndrome (PCOS) is shown to be associated with hyperandrogenemia and has some features such as cytotoxic T-cells activation and release of perforin and granzyme-B. Present work was aimed to investigate the relation of perforin and granzyme-B to androgenic state in PCOS.

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