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Association of Platelet Integrin αIIbβ3 Polymorphisms with Atherosclerotic Coronary Heart Disease in Sudanese Patients
Author(s) -
Lamyaa Ali Elsidege A,
Fathalrahman Mahdi Hass
Publication year - 2019
Publication title -
pakistan journal of biological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 43
eISSN - 1812-5735
pISSN - 1028-8880
DOI - 10.3923/pjbs.2019.335.341
Subject(s) - medicine , fibrinogen , genotyping , platelet , coronary heart disease , genotype , cardiology , body mass index , coronary artery disease , coronary atherosclerosis , gastroenterology , biology , biochemistry , gene
Glycoprotein IIIa and GPIIb constitutes are the fibrinogen receptor (integrin αIIbβ3). This glycoprotein has a fundamental role in atherothrombosis. This study aimed to detect the association of αIIbβ3 polymorphisms with atherosclerotic coronary heart disease in Sudanese patients and the association between the risk factors and platelet integrin αIIbβ3 polymorphisms.

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