Physio-chemical Characterization and Anti-microbial Activity of Serine Protease Inhibitors Purified from the Sophora japonica Seeds
Author(s) -
Mudasar Nabi,
Aaliya Bhat,
Shayaq ul Abeer Raso,
Sairish Ashraf,
Rouf Maqbool,
Showkat Gani,
Shajrul Amin
Publication year - 2018
Publication title -
pakistan journal of biological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 43
eISSN - 1812-5735
pISSN - 1028-8880
DOI - 10.3923/pjbs.2018.432.440
Subject(s) - protease , serine protease , ammonium sulfate precipitation , biochemistry , proteases , chemistry , molecular mass , biology , enzyme , chromatography , size exclusion chromatography
Protease inhibitors (PIs) regulate various cellular processes like cell cycle, differentiation, apoptosis and immune responses. Leguminous seeds are rich sources of protease inhibitors and many novel protease inhibitors have been purified from them. To isolate and purify protease inhibitors from seeds of Sophora japonica, characterize and investigate their anti- microbial activity.
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