Polymorphism of Glutamate-Cysteine Ligase Subunit Catalytic (GCLC) Gene in Pulmonary Tuberculosis Patients | Zendy

Ari Yuniastuti | Zendy; R. Susanti | Zendy; Dewi Mustikanin | Zendy

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Polymorphism of Glutamate-Cysteine Ligase Subunit Catalytic (GCLC) Gene in Pulmonary Tuberculosis Patients

Author(s) -

Ari Yuniastuti,

R. Susanti,

Dewi Mustikanin

Publication year - 2017

Publication title -

pakistan journal of biological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.268

H-Index - 43

eISSN - 1812-5735

pISSN - 1028-8880

DOI - 10.3923/pjbs.2017.397.402

Subject(s) - gclc , gclm , genotype , restriction fragment length polymorphism , microbiology and biotechnology , biology , polymerase chain reaction , oxidative stress , gene , dna ligase , genetics , biochemistry

The biomarker of oxidative stress in pulmonary tuberculosis patients has not been found. Oxidative stress occurs due to the low level of antioxidants. Single nucleotide polymorphism of glutamate-cysteine ligase subunit catalytic (GCLC) gene namely -129C/T GCLC has been reported to have an association with a risk factor of oxidative stress' susceptibility. The Objective of this study was to determine the GCLC polymorphism in pulmonary tuberculosis (TB) patient.

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