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Evaluation of MiR-21 and MiR-10b Expression of Human Breast Cancer in West Sumatera
Author(s) -
Yanwirasti Yanwirasti,
Wirsma Arif Harahap,
Dessy Arisanty
Publication year - 2017
Publication title -
pakistan journal of biological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 43
eISSN - 1812-5735
pISSN - 1028-8880
DOI - 10.3923/pjbs.2017.189.196
Subject(s) - microrna , breast cancer , carcinogenesis , real time polymerase chain reaction , biology , fibroadenoma , reverse transcription polymerase chain reaction , cancer , human breast , oncology , cancer research , messenger rna , gene , medicine , genetics
Abnormal expression of several microRNAs (miRNAs) has been demonstrated in many types of cancer tumor tissue. The miR-10b and miR-21 are an oncogenic miRNAs which play role in proliferation and invasion of Breast Cancer (BC) tumorigenesis. The aim of this study was to evaluate the miR-21 and miR-10b expression in BC in West Sumatran women, Indonesia.

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