Effect of Allogeneic Bone Marrow-mesenchymal Stem Cells (BM-MSCs) to Accelerate Burn Healing of Rat on the Expression of Collagen Type I and Integrin α2β1 | Zendy

Gusti Revilla | Zendy; Eryati Darwin | Zendy; Yanwirasti Yanwirasti | Zendy; Fedik Abdul Rantam | Zendy

Open Access

Effect of Allogeneic Bone Marrow-mesenchymal Stem Cells (BM-MSCs) to Accelerate Burn Healing of Rat on the Expression of Collagen Type I and Integrin α2β1

Author(s) -

Gusti Revilla,

Eryati Darwin,

Yanwirasti Yanwirasti,

Fedik Abdul Rantam

Publication year - 2016

Publication title -

pakistan journal of biological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.268

H-Index - 43

eISSN - 1812-5735

pISSN - 1028-8880

DOI - 10.3923/pjbs.2016.345.351

Subject(s) - mesenchymal stem cell , medicine , wound healing , bone marrow , type i collagen , angiogenesis , bone healing , stem cell , andrology , pathology , surgery , biology , genetics

Burn is a public health problem, it causes physical disability even death. Treatment of burn wound has been conducted in various ways, but the satisfactory healing has not been provided. Bone marrow-derived mesenchymal stem cells (BM-MSCs) treatment is one of attempt to burn recovery, accelerate wound healing and angiogenesis. This study aimed to investigate the effect of allogeneic BM-MSC treatment on the expression of collagen type I and integrin α2β1 in burn skin tissue of rat observed on day 14.

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