Open AccessMelatonin has favorable preventive effects on experimental chronic pancreatitis rat model
Author(s) -
Esra Güzel Tanoğlu,
Alpaslan Tanoğlu,
Makbule Çisel Aydin Meriçöz,
M. Fevzi Esen
Publication year - 2021
Publication title -
turkish journal of medical sciences
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-2103-134
Subject(s) - melatonin , medicine , endocrinology , oxidative stress , pancreatitis , placebo , intraperitoneal injection , pathology , alternative medicine
Currently, there is not any specific treatment for chronic pancreatitis (CP). It was aimed to investigate the effects of melatonin administration on endoplasmic reticulum (ER) stress, oxidative stress, fibrosis, biochemical and histopathological parameters, and Abcc2,Abcc5, and Abcg2 gene levels in an experimental rat CP model.