Open AccessEvaluation of serum CXC chemokine ligand 16 (CXCL16) as a novel inflammatory bio- marker or familial Mediterranean fever disease
Author(s) -
Taner Akyol,
Tolga Düzenli,
Alpaslan Tanoğlu
Publication year - 2021
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-2010-64
Subject(s) - cxcl16 , medicine , erythrocyte sedimentation rate , gastroenterology , chemokine , familial mediterranean fever , biomarker , c reactive protein , immunology , receiver operating characteristic , disease , cxcl10 , inflammation , biology , biochemistry
Familial Mediterranean fever (FMF) is a disease that is mainly diagnosed with clinical features. Several well- known inflammatory markers increase in FMF. However, there is still a need for diagnostic tests for specifying FMF and monitoring inflammatory activity. CXCL16 is a chemokine produced by inflammatory cells that demonstrate efficacy in the acute phase response. In this study, we aimed to investigate the relationship between CXCL16 levels and FMF disease and to evaluate CXCL16 levels as a novel biomarker for FMF.