Open AccessClinical predictors of drug-resistant epilepsy in children
Author(s) -
Pakize Karaoğlu,
Uluç Yış,
Ayşe Polat,
Müge Ayanoğlu,
Semra Hız
Publication year - 2021
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-2010-27
Subject(s) - medicine , epilepsy , status epilepticus , etiology , drug resistant epilepsy , pediatrics , abnormality , family history , comorbidity , neuroimaging , psychiatry
In up to 20% of epilepsy patients, seizures may not be controlled despite the use of antiepileptic drugs, either alone or in combination. These individuals are considered to have drug-resistant epilepsy. Drug-resistant epilepsy is usually associated with intellectual disability, psychiatric comorbidity, physical injury, sudden unexpected death, and low quality of life. Early detection and prediction of drug-resistant epilepsy are essential in determining the patient’s most appropriate treatment option. This retrospective study aimed to determine the clinical, electroencephalographic, and radiological factors associated with medically intractable childhood seizures.