Open AccessInvestigating differential miRNA expression profiling using serum and urine specimens for detecting potential biomarkers for early prostate cancer diagnosis
Author(s) -
Sevde Hasanoğlu,
Beyza Göncü,
Emrah Yücesan,
Sezen Atasoy,
Yunus Kayalı,
Nur Özten Kandaş
Publication year - 2021
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-2010-183
Subject(s) - urine , microrna , medicine , prostate cancer , urinary system , downregulation and upregulation , biomarker , cancer , prostate , biology , gene , genetics
MicroRNAs (miRNAs) are known up-to-date candidate biomarkers for several diseases. In addition, obtaining miRNA from different body fluids such as serum, plasma, saliva, and urine is relatively easy to handle. Herein we aimed to detect miRNAs as biomarkers for early stage prostate cancer (PC). For this purpose, we used urine and serum samples to detect any significant differences in miRNA profiles between patients and healthy controls.