Open AccessMEFV mutation frequencies in a Turkish cohort with low prevalence of familial Mediterranean fever
Author(s) -
Necati̇ Çakir,
Hülya Azaklı,
Duran Ustek,
Ömer Uysal,
Eren Gözke
Publication year - 2021
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-2009-119
Subject(s) - mefv , familial mediterranean fever , medicine , turkish population , cohort , gastroenterology , allele frequency , allele , confidence interval , population , gene mutation , mutation , genetics , gene , disease , genotype , biology , environmental health
Familial Mediterranean fever (FMF) is a genetically recessive autoinflammatory disease caused by mutations in the Mediterranean fever (MEFV) gene. The aim of this study was to investigate the frequencies of the most common MEFV mutations among a sample of healthy individuals from the Havsa population of European Turkey, where FMF is less prevalent compared to Asian Turkey.