Open AccessThe assessment of the serum levels of TWEAK and prostaglandin F2α in COVID – 19
Author(s) -
Demet Yalçın Kehribar,
Mustafa Cihangiroğlu,
Emine Sehmen,
Bahattin Avcı,
Mustafa Çapraz,
Maruf Boran,
Caner Günaydın,
Metin Özgen
Publication year - 2020
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-2006-96
Subject(s) - medicine , asymptomatic , immune system , immunology , lung , coronavirus , lymphocyte , disease , covid-19 , infectious disease (medical specialty)
It is claimed that aberrant immune response has a more important role than the cytopathic effect of the virus in the morbidity and mortality of the coronavirus disease 2019 (COVID-19). We aimed to investigate the possible roles of tumor necrosis factor-like weak inducer of apoptosis (TWEAK)/Fn14 pathway and leukotrienes (LT) in uncontrolled immune response that occurs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).