Open AccessEvaluation of saliva glutathione, glutathione peroxidase, and malondialdehyde levels in head-neck radiotherapy patients
Author(s) -
Gözde Derindağ,
Hayati Murat Akgül,
Ahmet Kızıltunç,
Halil İbrahim Özkan,
Hilal Kızıltunç Özmen,
Nilgün Akgül
Publication year - 2021
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-2006-84
Subject(s) - malondialdehyde , saliva , medicine , glutathione , glutathione peroxidase , radiation therapy , gastroenterology , oxidative stress , antioxidant , endocrinology , superoxide dismutase , enzyme , biochemistry , biology
It is believed that radiotherapy has important effects on oxidant/antioxidant systems. Oxidative stress occurs when the balance between oxidant formation and antioxidant defense is disrupted in favor of oxidants. The aim of this study was to determine the biochemical changes in saliva pre- and postradiotherapy in head-neck radiotherapy patients and to find out the effects of radiation on glutathione (GSH), glutathione peroxidase (GSH-Px), and malondialdehyde (MDA) levels in saliva.