Open AccessAssociation of trinucleotide repeat polymorphisms CAG and GGC in exon 1 of the Androgen Receptor gene with male infertility: a cross-sectional study
Author(s) -
Muhammad Waqar Ashraf,
Shahana Urooj Kazmi,
Hemaila Tariq,
Adnan Munir,
Rehana Rehman
Publication year - 2021
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-2005-74
Subject(s) - androgen receptor , medicine , infertility , male infertility , exon , sperm , andrology , gene , genetics , fertility , endocrinology , biology , population , cancer , prostate cancer , environmental health , pregnancy
Infertility is a global problem that brings with serious sexual and social consequences that strain the health sector and society. The expansion of CAG & GGC repeats in androgen receptor (AR) gene Ensembl number; ENSG169083 may leads to reduced fertility. Our objective was to determine association of CAG and GGC repeats with altered sperm parameters in male infertile subjects.