Open AccessA practical method of drug provocation testing to prove tolerance to alternative drugs in drug hypersensitivity
Author(s) -
Ebru Çelebioğlu,
Özge Öztürk Aktaş,
Gül Karakaya,
Fuat Kalyoncu
Publication year - 2021
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-2005-312
Subject(s) - medicine , provocation test , drug , drug tolerance , pharmacology , dermatology , alternative medicine , pathology
Drug provocation tests (DPTs) are the gold standard method performed at the end of a stepwise approach in a drug allergy workup. Drug provocation tests are administered as a single drug on a test day. Testing more than one drug in a day is a feasible option and could be a safe and time- and manpower-saving procedure in well-selected patients. The aim of the present study was to investigate the efficacy and safety of performing a DPT with two or three alternative drugs in one test day (Hacettepe method).