Open AccessRole of mir-33a, mir-203b, mir361-3p, and mir-424 in hepatocellular carcinoma
Author(s) -
Burhanettin Yalçınkaya,
Esra Güzel,
Didem Taştekin,
Sadrettin Pençe
Publication year - 2021
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-2004-214
Subject(s) - hepatocellular carcinoma , medicine , microrna , pathogenesis , biomarker , real time polymerase chain reaction , oncology , cancer , fold change , cancer research , gene , gastroenterology , gene expression , biology , genetics
Hepatocellular carcinoma (HCC) is one of the most aggressive cancer types. MicroRNAs (miRNAs) are small noncoding regulatory RNAs that function posttranscriptionally. miRNA deregulation was observed in the development and progression of HCC. In this study, we aimed to investigate the expression levels of four miRNAs (mir-33a, mir-203b, mir361-3p, and mir-424) in HCC patients in comparison to healthy individuals.