Open AccessEffect of prenatal exposure to cigarette smoke on the conduction of sensory nerve fibers in the rat
Author(s) -
Jumah Shakhanbeh
Publication year - 2012
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-1104-19
Subject(s) - medicine , nerve conduction velocity , offspring , sensory nerve , sensory system , cigarette smoke , prenatal exposure , stimulation , anesthesia , anatomy , pregnancy , neuroscience , biology , genetics , environmental health
doi:10.3906/sag-1104-19 Eff ect of prenatal exposure to cigarette smoke on the conduction of sensory nerve fi bers in the rat Jumah SHAKHANBEH Aim: To investigate the eff ect of prenatal exposure to cigarette smoke (CS) on the conduction of sensory nerve fi bers in the adult rat off spring. Materials and methods: Pregnant rats were exposed to CS by inhalation during the gestation period. Th e saphenous nerve in the adult off spring was exposed in vivo, and the conduction parameters of the threshold, maximum strength of stimulation, conduction velocity, and amplitude of compound action potentials (CAPs) of Aαβ-, Aδ-, and C-fi bers were examined. Results: Prenatal exposure to CS induced signifi cant reduction (P < 0.005) in the peak amplitude of CAPs of Aαβ- and Aδ-fi bers. Th e conduction velocity of Aαβ-fi bers and C-fi bers was signifi cantly (P < 0.025-0.05) increased aft er prenatal exposure to CS. Conclusion: Prenatal exposure to CS attenuates the conduction of sensory nerve fi bers in the rat saphenous nerve