Open AccessPostoperative atrial fibrillation, oxidative stress, and inflammation
Author(s) -
Mehmet Özaydın
Publication year - 2011
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-1003-691
Subject(s) - atrial fibrillation , medicine , oxidative stress , inflammation , complication , pathophysiology , randomized controlled trial , cardiology , anesthesia
doi:10.3906/sag-1003-691 Postoperative atrial fi brillation, oxidative stress, and infl ammation Mehmet ÖZAYDIN Abstract: Postoperative atrial fi brillation is the most common complication of cardiac surgery. It is associated with increased complication rates. Recent trials have suggested that infl ammation and oxidative stress have key roles in the pathophysiology of atrial fi brillation. Current evidence evaluating the use of antiinfl ammatory and antioxidant agents, including statins, corticosteroids, N-acetylcysteine, vitamin C, and fi sh oil, to prevent postoperative atrial fi brillation is promising. However, larger randomized, controlled trials comparing diff erent dose regimens are needed. Key words: Coronary artery bypass graft s, atrial fi brillation, infl ammation, oxidative stress Postoperatif atriyal fi brilasyon, infl amasyon ve oksidatif stress Özet: Postoperatif atriyal fi brilasyon kardiyak cerrahinin en sık görülen komplikasyonudur ve artmış komplikasyon risk