
The effect of experimentally induced carbon dioxide pneumoperitoneum on intra-abdominal and intra-esophageal pH
Author(s) -
Tutku Soyer,
Tolga Reşat Aydos,
Zühal Aktuna,
Oğuzhan Korkut,
Gökhan Osmanoğlu,
Öymen Hançerlioğulları,
Murat Çakmak
Publication year - 2009
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-0807-18
Subject(s) - pneumoperitoneum , medicine , insufflation , anesthesia , catheter , abdomen , abdominal cavity , umbilicus (mollusc) , esophagus , carbon dioxide , laparoscopy , surgery , ecology , biology
doi:10.3906/sag-0807-18 The effect of experimentally induced carbon dioxide pneumoperitoneum on intra-abdominal and intra-esophageal pH Aim: An experimental study was performed to evaluate the effect of CO2 pneumoperitoneum on intra-abdominal (IA) and intra-esophageal (IE) pH. Material and methods: The study included 18 Wistar rats. In the control group (n = 6) a pH catheter was inserted into the peritoneal cavity via a left upper quadrant incision and another catheter was inserted into the lower esophagus via the oral route. Pre- and post-insufflation IA and IE pH were recorded every 5 min for 1 h. In the experimental groups, in addition to pH catheters, a 16-G catheter was inserted into the abdomen above the umbilicus. In the O2 group (n = 6) 95 % O2 and 5 % CO2 were insufflated with a pressure of 10 mmHg. In the CO2 group (n = 6), CO2 was insufflated with the same pressure and duration. Results: In the CO2 group, IA and IE pH values significantly decreased (P < 0.05). IA pH values decreased in the CO2 group when compared to the control and O2 groups (P < 0.05). There was not a significant difference in IE pH between the CO2 group and the other groups. Conclusion: CO2 insufflation decreased IA pH values. Decreased pH values obtained with continuous recordings of the esophagus may have been related to increases in intra-abdominal pressure, rather than the metabolic effects of CO2 pneumoperitoneum