Open AccessAllergen-Specific Immunotherapy Against Allergic Respiratory Diseases
Author(s) -
강성윤,
양민석,
이상민,
이상표
Publication year - 2020
Publication title -
the korean journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 2289-0769
pISSN - 1738-9364
DOI - 10.3904/kjm.2020.95.6.370
Subject(s) - medicine , asthma , immunotherapy , allergic asthma , immunology , allergen , allergy , placebo , clinical trial , allergen immunotherapy , respiratory system , intensive care medicine , immune system , pathology , alternative medicine
Allergen-specific immunotherapy (AIT) can alter the natural course of an allergic disease. It is widely held that the efficacy of a given therapeutic modality should be proven by well-designed double-blind placebo-controlled randomized clinical trials and meta-analyses. In this article, the therapeutic efficacy of AIT for allergic respiratory diseases, such as allergic rhinitis and asthma, is reviewed. In addition, potential clinical and experimental predictors of the treatment response are reviewed for AITs requiring long-term treatment, and for some allergic rhinitis and asthma patients who show no response to AIT.