Pan‑RAF inhibitor LY3009120 is highly synergistic with low‑dose cytarabine, but not azacitidine, in acute myeloid leukemia withRASmutations
Author(s) -
Jihyun Park,
Hyejoo Park,
Ja Min Byun,
Junshik Hong,
DongYeop Shin,
Youngil Koh,
SungSoo Yoon
Publication year - 2021
Publication title -
oncology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 54
eISSN - 1792-1082
pISSN - 1792-1074
DOI - 10.3892/ol.2021.13006
Subject(s) - cytarabine , myeloid leukemia , cancer research , azacitidine , neuroblastoma ras viral oncogene homolog , kras , cell cycle , leukemia , myeloid , apoptosis , mapk/erk pathway , medicine , pharmacology , biology , immunology , cancer , kinase , biochemistry , gene expression , colorectal cancer , dna methylation , gene , microbiology and biotechnology
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