Open AccessLarge moderately-differentiated ovarian Sertoli-Leydig cell tumor in a 13-year-old female: A case report
Author(s) -
Hui Zhang,
Jing Hao,
ChunYan Li,
Tao Li,
Yuguang Mu
Publication year - 2015
Publication title -
oncology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 54
eISSN - 1792-1082
pISSN - 1792-1074
DOI - 10.3892/ol.2015.3979
Subject(s) - ovary , sertoli cell , ovarian tumor , oophorectomy , medicine , leydig cell , leydig cell tumor , stromal cell , biology , pathology , hormone , spermatogenesis , ovarian cancer , cancer , luteinizing hormone , hysterectomy
Sertoli-Leydig cell tumor of the ovary, also known as androblastoma, is a rare neoplasm from the group of sex cord-stromal tumors of the ovary. The tumor accounts for <0.5% of all primary ovarian neoplasms. The clinical signs and symptoms of Sertoli-Leydig cell tumors can be associated with either hormonal production or the presence of a mass-occupying lesion. In the current study, a 13-year-old female was diagnosed with a stage Ic ovarian Sertoli-Leydig cell tumor following abdominal pain and distension. One month after a right oophorectomy, the follow-up magnetic resonance imaging scan was negative for residual or recurrent tumor. The overall 5-year survival rate for moderately-differentiated (grade 2) and poorly-differentiated (grade 3) Sertoli-Leydig cell tumors is 80%, and long-term follow-up is therefore highly advised in this patient.