Open AccessGlomus tumor of the shoulder: A case report and review of the literature
Author(s) -
Agnese Proietti,
Greta Alì,
Francesca Quilici,
Pietro Bertoglio,
Alfredo Mussi,
Gabriella Fontanini
Publication year - 2013
Publication title -
oncology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 54
eISSN - 1792-1082
pISSN - 1792-1074
DOI - 10.3892/ol.2013.1478
Subject(s) - glomus tumor , pathology , glomus cell , lesion , medicine , immunohistochemistry , cd34 , soft tissue , neoplasm , anatomy , biology , surgery , carotid body , stem cell , carotid arteries , genetics
Glomus tumors are benign neoplasms that arise from neuromyoarterial glomus bodies, with clinical manifestations that include acute pain, cold intolerance and tenderness. Glomus tumors may occur anywhere in the skin, soft tissue or gastrointestinal tract, but are most frequently encountered in the nail bed of the hands. The present study reports the case of a 30-year-old female with a history of shoulder pain caused by a cystic neoformation. Following surgery, a microscopic examination revealed nests of small cells of a rounded and regular shape. The tumor cells exhibited positive expression for CD34 and smooth muscle actin. This study supports and confirms the fact that a glomus tumor is a benign neoplasm that may occur in multiple locations. Therefore, the significance of a histological and immunohistochemical approach for a correct characterization of this lesion is required.