Open AccessSarcomatoid carcinoma of the pancreas: A case report and review of the literature
Author(s) -
Ying Xie,
Yien Xiang,
Dan Zhang,
Xiaoxiao Yao,
Jiyao Sheng,
Yongsheng Yang,
Xuewen Zhang
Publication year - 2018
Publication title -
molecular medicine reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.727
H-Index - 56
eISSN - 1791-3004
pISSN - 1791-2997
DOI - 10.3892/mmr.2018.9489
Subject(s) - histopathology , pancreas , jaundice , medicine , bile duct , sarcomatoid carcinoma , carcinoma , oncogene , pathology , common bile duct , immunohistochemistry , neoplasm , general surgery , radiology , gastroenterology , cancer , cell cycle
Sarcomatoid carcinoma (SC) is an extremely rare and complicated malignant neoplasm that consists of both malignant epithelial components and atypical spindle cells that express an epithelial phenotype. The presents study reported a case of SC of the pancreas (SCP), along with a brief review of the literature. A 63‑year‑old man was admitted to The Second Hospital of Jilin University hospital with complaints of epigastralgia and jaundice of one month in duration. Based on preoperative laboratory blood tests and radiography, a mass at the distal common bile duct was suspected. Intraoperative examination discovered a 2.5x2x1.8‑cm mass in the pancreatic head, with invasion of the distal bile duct. Pancreaticoduodectomy was performed. Histopathology and immunohistochemistry of the specimen confirmed the diagnosis of SCP. The patient succumbed 18 months after surgery due to multiple hepatic metastases.