Open AccessSuppression of A549 cell proliferation and metastasis by calycosin via inhibition of the PKC-α/ERK1/2 pathway: An in vitro investigation
Author(s) -
XU-DONG CHENG,
JUN-FEI GU,
JIA-RUI YUAN,
Feng Liang,
XIAO-BIN JIA
Publication year - 2016
Publication title -
molecular medicine reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.727
H-Index - 56
eISSN - 1791-3004
pISSN - 1791-2997
DOI - 10.3892/mmr.2016.4976
Subject(s) - mistake , cell cycle , calycosin , oncogene , in vitro , apoptosis , staurosporine , microbiology and biotechnology , chemistry , cancer research , biology , protein kinase c , kinase , biochemistry , genetics , political science , daidzein , formononetin , genistein , law
Mol Med Rep 12:[Related article:] 7992–8002, 2015; DOI: 10.3892/mmr.2015.4449 Following the publication of this article, an interested reader drew to our attention an anomaly associated with the presentation of Fig. 2; essentially, an image had been inadvertently selected from the same original photomicrograph to represent Fig. 2D, the centre panel [+80 nM phorbol-12-myristate-13-acetate (TPA), + 20 μM calycosin (Cal)] and Fig. 2F, the second panel from the right (+ 80 nM TPA, + 30 μM Cal). After having re-examined our original data, the panel originally featured in Fig. 2F was identified as having been selected incorrectly for the Figure. A corrected version of Fig. 2 is presented on next page, which features the proper data for Fig. 2F. Fig. 2D and F showed the effect of different concentrations of Cal on the migration and invasive ability of the TPA-treated A549 cells, respectively; Cal was demonstrated to inhibit the migration, and to suppress the invasive ability, of the A549 cells induced by TPA. Therefore, this error did not affect the overall conclusions reported in the present study. We sincerely apologize for this mistake, and thank the reader of our article who drew this matter to our attention. Furthermore, we regret any inconvenience this mistake has caused.