Open AccessIntraductal papillary‑mucinous carcinoma with portal vein tumor thrombus and multifocal liver metastasis: An autopsy case
Author(s) -
Naohiro Matsushita,
Akitoshi Douhara,
Hirotsugu Ueno,
Shohei Asada,
Kōji Murata,
Koji Yanase,
Masahiro Tsutsumi
Publication year - 2021
Publication title -
molecular and clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.442
H-Index - 7
eISSN - 2049-9469
pISSN - 2049-9450
DOI - 10.3892/mco.2021.2263
Subject(s) - medicine , metastasis , autopsy , pathology , papillary adenocarcinoma , thrombus , cancer , adenocarcinoma , radiology
The prognosis of intraductal papillary-mucinous neoplasm is superior to that of conventional pancreatic ductal adenocarcinoma. Only a few advanced cases of intraductal papillary-mucinous carcinoma (IPMC) have been reported to date. We herein report the case of a 78-year-old male patient with advanced pancreatobiliary type IPMC with portal vein invasion and liver metastasis. The IPMC invaded the portal vein to form a tumor thrombus and it also metastasized to the liver via the portal vein. After receiving best supportive care, the patient succumbed to the disease following an exacerbation of IPMC 90 days after the initial presentation. On autopsy, a very long tumor thrombus was identified, along with liver metastatic lesions, which had retained the structure of the primary IPMC on histological examination.