Open AccessUsefulness of palliative prognostic score in the treatment of patients with non-resectable gastric cancer
Author(s) -
Masahide Ikeguchi,
Abdul Kader,
M Yoshimoto,
Seigo Takaya,
Junya Watanabe,
Yoshihiro Fukumoto,
Tomohiro Osaki,
Hiroaki Saito,
Shigeru Tatebe,
Toshiro Wakatsuki
Publication year - 2013
Publication title -
molecular and clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.442
H-Index - 7
eISSN - 2049-9469
pISSN - 2049-9450
DOI - 10.3892/mco.2013.66
Subject(s) - medicine , docetaxel , cancer , regimen , chemotherapy , oncology
The aim of this study was to evaluate the clinical usefulness of the palliative prognostic (PaP) score in patients with non-resectable advanced gastric cancer. The PaP score was calculated prior to each course of chemotherapy in 44 consecutive patients with non-resectable advanced gastric cancer between 2003 and 2010 at the Tottori University Hospital, Yonago, Japan. The prognosis was evaluated according to the PaP score and the different chemotherapeutic agents. The median survival time (MST) was 10 months. The PaP score classified the heterogeneous patient sample into three isoprognostic groups with regard to the possibility of a 1-month survival period, with 28 patients in group A (>70% chance), 12 in group B (30-70% chance) and 4 in group C (<30% chance). The MST of the three groups was 11, 3 and 1 months for group A, B and C, respectively. In group A, chemotherapeutic regimens did not affect patient survival, although the docetaxel regimen prolonged survival of patients in group B. In conclusion, the PaP score may be useful in selecting the best chemotherapeutic regimen in patients with non-resectable gastric cancer.