
Constitutive activation of p70 S6 kinase is associated with intrinsic resistance to cisplatin
Author(s) -
Rohini Dhar,
Alakananda Basu
Publication year - 2008
Publication title -
international journal of oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.405
H-Index - 122
ISSN - 1019-6439
DOI - 10.3892/ijo.32.5.1133
Subject(s) - cisplatin , p70 s6 kinase 1 , cancer research , ly294002 , downregulation and upregulation , pi3k/akt/mtor pathway , parp inhibitor , poly adp ribose polymerase , kinase , mapk/erk pathway , cell cycle , biology , cell growth , apoptosis , chemistry , microbiology and biotechnology , signal transduction , polymerase , chemotherapy , biochemistry , genetics , gene