Open AccessSuppression of hepatocyte CYP1A2 expression by Kupffer cells via AhR pathway: The central role of proinflammatory cytokines
Author(s) -
Rongqian Wu,
Xiaoxuan Cui,
Weifeng Dong,
Mian Zhou,
Henry S. Simms,
Ping Wang
Publication year - 2006
Publication title -
international journal of molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.048
H-Index - 90
eISSN - 1791-244X
pISSN - 1107-3756
DOI - 10.3892/ijmm.18.2.339
Subject(s) - proinflammatory cytokine , cyp1a2 , aryl hydrocarbon receptor , downregulation and upregulation , sepsis , tumor necrosis factor alpha , hepatocyte , biology , lipopolysaccharide , chemistry , pharmacology , immunology , cancer research , cytochrome p450 , inflammation , endocrinology , transcription factor , biochemistry , metabolism , gene , in vitro