Open Access
mTORC1 is a key regulator that mediates OGD‑ and TGFβ1‑induced myofibroblast transformation and chondroitin‑4‑sulfate expression in cardiac fibroblasts
Author(s) -
Chao Li,
Zheng Zhang,
Peng Yu,
Yanying Zhang,
Wanrong Kang,
Yingdong Li,
Hai Yang
Publication year - 2022
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2022.11340
Subject(s) - myofibroblast , pi3k/akt/mtor pathway , mtorc1 , protein kinase b , cardiac fibrosis , microbiology and biotechnology , blot , gene knockdown , viability assay , biology , cancer research , signal transduction , chemistry , fibrosis , cell , medicine , apoptosis , biochemistry , gene