Open AccessMetformin reduces chondrocyte pyroptosis in an osteoarthritis mouse model by inhibiting NLRP3 inflammasome activation
Author(s) -
Jiangbo Yan,
Dong Ding,
Gangning Feng,
Yong Yang,
Yong Zhou,
Long Ma,
Hua Guo,
Zan Lü,
Qunhua Jin
Publication year - 2022
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2022.11146
Subject(s) - metformin , osteoarthritis , pyroptosis , medicine , cartilage , staining , matrix metalloproteinase , inflammasome , chondrocyte , endocrinology , pathology , diabetes mellitus , receptor , anatomy , alternative medicine