Open AccessHirudin, a thrombin inhibitor, attenuates TGF-β-induced fibrosis in renal proximal tubular epithelial cells by inhibition of protease-activated receptor 1 expression via S1P/S1PR2/S1PR3 signaling
Author(s) -
Qiang Lin,
Chunli Long,
Zhengang Wang,
Ronghui Wang,
Wei Shi,
Jiwei Qiu,
Junlin Mo,
Yongxiang Xie
Publication year - 2021
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2021.10924
Subject(s) - hirudin , biology , fibrosis , thrombin , cancer research , chemistry , medicine , immunology , platelet