Open AccessMetformin attenuates H2O2‑induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway
Author(s) -
Keda Yang,
Lei Pei,
Siming Zhou,
Tao Lin,
Yue Zhu
Publication year - 2021
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2021.10751
Subject(s) - apoptosis , metformin , gene knockdown , sirt3 , medicine , osteoblast , endocrinology , pi3k/akt/mtor pathway , biology , viability assay , oxidative stress , protein kinase b , ovariectomized rat , osteoporosis , estrogen , sirtuin , enzyme , biochemistry , in vitro , insulin , nad+ kinase