Open AccessSinomenine hydrochloride ameliorates dextran sulfate sodium‑induced colitis in mice by modulating the gut microbiota composition whilst suppressing the activation of the NLRP3 inflammasome
Author(s) -
Yan Zhou,
Shuai Chen,
Wei Gu,
Xiao Sun,
Linxiao Wang,
Liming Tang
Publication year - 2021
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2021.10722
Subject(s) - sinomenine , colitis , inflammasome , chemistry , proinflammatory cytokine , pharmacology , gut flora , inflammation , spleen , inflammatory bowel disease , nitric oxide , nitric oxide synthase , immunology , microbiology and biotechnology , biochemistry , biology , medicine , disease , organic chemistry