Open AccessLithium chloride ameliorated spatial cognitive impairment through activating mTOR phosphorylation and inhibiting excessive autophagy in the repeated cerebral ischemia‑reperfusion mouse model
Author(s) -
Yining Xiao,
Mingyue Fan,
Wei Jin,
William A Li,
Yanqiu Jia,
Yanhong Dong,
Xin Jiang,
Jing Xu,
Nan Meng,
Peiyuan Lv
Publication year - 2020
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2020.9237
Subject(s) - nissl body , morris water navigation task , hippocampus , autophagy , pi3k/akt/mtor pathway , lithium chloride , water maze , ischemia , memory impairment , hippocampal formation , neuroscience , blot , pharmacology , medicine , endocrinology , pathology , chemistry , apoptosis , biology , staining , cognition , biochemistry , organic chemistry , gene