Open AccessIGF‑1 induces cellular senescence in rat articular chondrocytes via Akt pathway activation
Author(s) -
Liang Zhao,
L. Beijers-De Bie,
Lan Hu,
Zihan Zhu,
Xinghua Meng,
Linlin Cong,
Shai Zhang,
Ning Ma,
Jianhua Xiao
Publication year - 2020
Publication title -
experimental and therapeutic medicine
Language(s) - Uncategorized
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2020.9177
Subject(s) - senescence , microbiology and biotechnology , protein kinase b , chondrocyte , cell cycle , pi3k/akt/mtor pathway , cell growth , downregulation and upregulation , biology , growth factor , signal transduction , chemistry , cell , cartilage , biochemistry , anatomy , receptor , gene