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Epigenetic modulation of the MAPK pathway prevents isoflurane‑induced neuronal apoptosis and cognitive decline in aged rats
Author(s) -
Lei Huang,
Haibin Fang,
Hui Cheng,
Shenglan Mei,
YunPing Cheng,
Yao Lv,
Qingtao Meng,
Zhongyuan Xia
Publication year - 2020
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2020.9162
Subject(s) - isoflurane , morris water navigation task , apoptosis , tunel assay , p38 mitogen activated protein kinases , hippocampus , western blot , anesthetic , mapk/erk pathway , medicine , pharmacology , endocrinology , chemistry , signal transduction , anesthesia , biochemistry , gene