Open AccessSuccessful treatment of a 12‑year‑old boy with Guillain‑Barr� syndrome requiring tracheostomy due to respiratory muscle paralysis: A case report
Author(s) -
Manabu Miyamoto,
George Imataka,
Go Ichikawa,
Yutaka Saito,
Takashi Kashiwagi,
Yoshiyuki Kaji,
Koji Wake,
Kengo Funakoshi,
Takahide Nagashima,
Norito Kokubun,
Shigemi Yoshihara
Publication year - 2019
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2019.8311
Subject(s) - medicine , guillain barre syndrome , paralysis , respiratory system , respiratory failure , tracheal intubation , mechanical ventilation , intubation , anesthesia , pediatrics , surgery
Childhood Guillain-Barré syndrome (GBS) occasionally leads to respiratory failure early after onset, requiring long-term ventilation management after tracheal intubation. However, patients requiring tracheostomy management are rare. In the present study, a case of a 12-year-old boy with GBS who required artificial respiration management due to rapid progression of respiratory muscle paralysis is reported. Intravenous immunoglobulin (IVIg) and pulse steroid therapy were provided; however, both were ineffective and tracheostomy was necessary 26 days after onset. A second course of IVIg and pulse steroid therapy was administered on day 34. With continued rehabilitation, the patient was able to walk long distances on day 74 and was subsequently discharged on day 89. In cases of severe GBS, when IVIg and pulse steroid therapy do not improve the respiratory muscle strength of the patient, early tracheostomy may improve the patient's quality of life during artificial respiration management.