Open AccessBronchopulmonary dysplasia: Pathogenesis and treatment (Review)
Author(s) -
Asfia Banu Pasha,
Xiaoqing Chen,
Guoping Zhou
Publication year - 2018
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2018.6780
Subject(s) - bronchopulmonary dysplasia , medicine , pathogenesis , respiratory distress , incidence (geometry) , intensive care medicine , disease , pediatrics , surgery , biology , pregnancy , genetics , gestational age , physics , optics
Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease of infancy, which mostly affects premature infants with significant morbidity and mortality. Premature infants who require to be treated for conditions including respiratory distress syndrome have a higher risk of developing BPD. In spite of the improvement in clinical methods, the incidence of BPD has not reduced. In the present review, the pathogenesis of BPD is described along with the treatments available at present and the role of nursing in the management of BPD. Emerging preventive therapies for BPD are also discussed, including the use of recombinant human superoxide dismutase, which has been proven effective in reducing respiratory injury and its long-term effects.