Open AccessPurulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption
Author(s) -
Lunfei Liu,
Yan Jiao,
Jianyou Wang,
Jisu Chen,
Sheng Cai,
Limin Lao,
Min Zheng
Publication year - 2013
Publication title -
experimental and therapeutic medicine
Language(s) - English
Resource type - Journals
eISSN - 1792-1015
pISSN - 1792-0981
DOI - 10.3892/etm.2013.944
Subject(s) - toxic epidermal necrolysis , acute generalized exanthematous pustulosis , dermatology , drug eruption , bulla (seal) , medicine , drug , drug reaction , adverse drug reaction , pathology , pharmacology , lung
Drug eruption is a major problem of adverse drug reactions and may present as variform clinical manifestations. Toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP) are relatively rare severe drug eruptions. It has rarely been reported that AGEP overlaps or mimics TEN, while no purulent bullous epidermal necrolysis has been reported. The present study reports a rare case of an adult female patient with the clinical manifestations of purulent bulla and epidermal necrolysis caused by drug ingestion. The case is discussed to reveal whether a new clinical pattern of drug eruption has been identified.