Open AccessApplication of Chitosan and Hydroxyapatite in Periodontal Tissue Regeneration: A Review
Author(s) -
Asdar Gani,
Risfah Yulianti,
Supiaty Supiaty,
Machirah Rusdy
Publication year - 2022
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2022.8423
Subject(s) - medicine , periodontium , dentistry , periodontitis , chronic periodontitis , regeneration (biology) , periodontal disease , chitosan , biocompatibility , bone tissue , tissue engineering , biomedical engineering , biochemistry , chemistry , materials science , metallurgy , biology , microbiology and biotechnology
Chronic periodontitis is an infection caused by bacteria in the gum tissue that supports the teeth. The current periodontal therapy manages or removes periodontal infections and repairs the periodontium destroyed due to periodontal disease. Due to its biodegradability and biocompatibility, chitosan (CH) and hydroxyapatite (HAP) are employed for bone tissue healing. The purpose of this study was to compare the utilization of CH and HAP in the regeneration of periodontal tissue. The presented study is a systematic review prepared from a collection of recent relevant published articles. This research was conducted by reviewing articles from 2016 to August 2021. The analysis found that CH/HAP is a therapeutic strategy for chronic periodontitis patients that allow low-cost bone regeneration, mHA/CH scaffolds may inhibit the growth of periodontal pathogens, and CH or HAP has the potential to be developed bone tissue engineering.