Open AccessRenal AML Surgically Treated 33 Cases
Author(s) -
Mohamed Salama,
A.M.A. Mostafa,
Nada Mohsen Salama,
Mona Alabrak,
Shaimaa Abdalaleem Abdalgeleel,
Ayman Hanafy
Publication year - 2022
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2022.7300
Subject(s) - medicine , tuberous sclerosis , nephrectomy , angiomyolipoma , lymphangioleiomyomatosis , surgery , kidney , medical record , radiology
BACKGROUND: Renal angiomyolipoma (RAML) is a rare benign neoplasm with a prevalence varying between 0.2% and 0.6% and a strong female predilection. They occur as sporadic, isolated entities in 80% of cases. The remaining 20% of angiomyolipomas (AMLs) develop in association with tuberous sclerosis complex or pulmonary lymphangioleiomyomatosis.AIM: We describe our 10-year experience with AML and discuss the treatment strategies employed at our center.METHODS: The medical records of all 33 patients with pathologically confirmed RAML treated either by nephrectomy or nephron-sparing surgery at our center over 10 years were reviewed for patient age and sex, tumor location and size, association with TBS.RESULTS: There were 28 females (84.8%) and 5 males (15.2%) with a median age that was 52 (range 22–74) years at the time of surgery. Thirty patients (90.9%) had sporadic isolated AML, and 3 patients (9.1%) had AML with TBS. The tumor was in the right kidney in 15 (45.5%) patients, in the left kidney in 17 (51.5%) patients, and bilateral in only 1 patient (3%) who was diagnosed with TBS. At presentation, flank pain was the main symptom in 23 patients (69.7%).CONCLUSIONS: Surgical resection of RAML provides short-term symptomatic relieve and long-term survival.