Open AccessCardiac Biomarkers in hypertensive disorders of pregnancy
Author(s) -
Dolina Gencheva,
Fedya Nikolov,
E Uchikova,
Krasimira Hristová,
Rosen Mihaylov,
Blagovesta Pencheva
Publication year - 2021
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2021.5913
Subject(s) - medicine , pregnancy , cardiology , disease , stroke (engine) , gdf15 , acute coronary syndrome , coronary artery disease , biomarker , intensive care medicine , myocardial infarction , chemistry , genetics , engineering , biology , mechanical engineering , biochemistry
In recent years, biomarkers have taken a central place in the assessment of cardiovascular diseases – from prediction to management and prognosis. On the other hand, enough evidence exists to assume that hypertensive disorders of pregnancy share a certain connection with cardiovascular diseases – from common risk factors and underlying mechanisms to the presence of a higher risk for women for the development of a great number of cardiovascular diseases, such as arterial hypertension, coronary atherosclerosis, stroke, peripheral artery disease, venous thromboembolism, and even a higher cardiovascular mortality. The key to a better understanding of the unfavorable cardiovascular profile of women with a hypertensive disorder of pregnancy may lie in their assessment with biomarkers, typically used in the field of cardiology. In this review, we have included studies investigating the use of cardiovascular biomarkers during or after a hypertensive pregnancy, namely, natriuretic peptides, high-sensitivity cardiac troponins, growth/differentiation factor 15 (GDF15), soluble suppression of tumorigenicity-2 (sST2), and galectin-3.