Open AccessMyringoplasty with Morphological Rationale of Application of Xenoperitoneum Decellularized Matrix in Experiment
Author(s) -
Dias Yesniyazov,
Maida Tussupbekova,
Н Т Абатов,
Yekaterina Yukhnevich,
R. M. Badyrov
Publication year - 2021
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2021.5897
Subject(s) - decellularization , myringoplasty , medicine , matrix (chemical analysis) , connective tissue , surgery , tympanoplasty , biomedical engineering , tissue engineering , pathology , materials science , composite material
AIM: The aim of the study is to create a myringoplasty technique with decellularized matrix of xenoperitoneum in an experiment on rabbits with morphological rationale of a new biological material application.
METHODS:
Sixty rabbits were included in research. The animals were randomly divided in two groups for use the bioimplant – decellularized matrix of xenoperitoneum and control. Each subgroup corresponded to the observation period and the removal of the animal from the experiment. Observation period was: 7 days, 21 days and 30 days after myringoplasty.
RESULT:
The maturation of connective tissue in both groups was completed by the 30th day. But the change in the exudative phase into the proliferative phase occurred faster and the dynamics of reparative processes after myringoplasty were better in experimental group.
CONCLUSION:
The use the decellularized matrix of xenoperitoneum had better reparative properties